Tips for NTx testing
At the Center for Better Bones, Dr. Susan Brown uses the Osteomark NTx urine test
to determine if her patients are undergoing excessive bone loss. Here are some of
- Strive for the average premenopausal value:
36 bone collagen equivalent units/mmol creatinine. (The range is
- To check your progress, do follow-up tests every 6–12 months.
- In general, a number somewhere between 30 to the mid-40’s bone collagen equivalent
units/mmol creatinine should indicate a safe amount of bone turnover.
One of the most useful medical tests for bone health
assesses the rate of bone breakdown, a process known as bone resorption.
Bone is living tissue where many minerals are embedded. And as bone breaks down,
its by-products appear in the urine and blood. By measuring these bone by-products,
the N-telopeptide or NTx test is one new way to evaluate the rate
at which your bones are undergoing bone resorption.
This test because it provides a dynamic measurement of what is actually happening
inside the bone at any given time. Bone density as
measured by DEXA, on the other hand, provides a static, snapshot of your
bones, and doesn’t distinguish if bone loss is ongoing or not. While a certain
amount of bone breakdown is perfectly normal, a high rate of bone breakdown suggests
that there may be long-term bone loss and, in time, a
greater risk for fracture.
The NTx test can measure N-telopeptide levels in the urine or blood. The box at
right indicates a healthy range to strive for. NTx tests are also used by healthcare
providers to determine whether antiresorptive medications, such as
Fosamax, are stopping excessive bone breakdown.
Start reducing your risk
of bone loss and fracture