Many women’s bodies react to hormonal fluctuations
with head pain, often in a cyclical fashion that corresponds to the monthly ebb
and flow of estrogen and progesterone. Conventional doctors and headache specialists
often overlook this common headache trigger, and even when they don’t, little is
offered in the way of long-term solutions. Most primary care physicians will write
a prescription for a pain reliever or birth control pills or refer these patients
to their ob-gyn.
I am happy to report that many women find their headaches become less frequent or
disappear altogether once they address their hormonal imbalance through diet, optimal
nutrition, and sometimes short-term bioidentical hormonal supplementation.
Even if headaches have never been a concern for them before, many women may become
more sensitive to their own hormones as they get older. As they enter perimenopause,
women may begin to experience hormonal headaches or menstrual migraines for the
first time. The majority of these women experience a dramatic improvement in their
headaches post menopause.
Addressing the root causes of hormonal headaches and migraines with a holistic approach
can be effective. It can take a bit longer than popping a pill, but I assure you,
there are many additional, long-term benefits following relief from your headache.
Who gets hormonal headaches?
Women who are susceptible to hormonal fluctuations often suffer with menstrual headaches
or migraines just prior to the onset of menses when there is a natural drop in progesterone
levels. But headaches may also occur when estrogen and other hormones spike, or
during menses itself, when estrogen and progesterone have bottomed out.
Hormonal headaches can come on suddenly or become more unpredictable in perimenopause
or at menopause, when hormones are really shifting. Some women who have never experienced
headache or migraine before begin to suffer with regularity. In my practice, I have
seen women with incapacitating migraines in their initial year of menopause, similar
to those they recall experiencing at puberty/menarche. But for the 40 years in between,
they had no headache pain! Every woman is different, and tuning into your body’s
own unique signals is the first step in any kind of natural prevention or treatment.
As with any other kind of headache or migraine, tracking the onset of your pain
using a journal will help you get a handle on any pattern and potential cause. If
you are still menstruating, I recommend charting the days of your period for a few
months with the same journal. This will help you understand the basic ebb and flow
of hormones in your system each month and how these may relate to your headache
You should be aware that most headaches are multifactorial and may have overlapping
triggers. Hormones are often part of the headache/migraine cascade, even if they
haven’t been officially identified. Any woman with regular headaches or migraines
can benefit from improving her overall ratio of estrogen and progesterone.
The estrogen–progesterone connection
Most hormonal headaches occur when levels of estrogen are out of balance in relation
to natural levels of progesterone. As noted above, for many women this may be correlated
with the naturally lower levels of progesterone that are normal before their period
starts, when progesterone levels naturally drop off. Or less frequently, it may
be a state of true progesterone deficiency because some women, especially during
perimenopause and menopause, may have unnaturally low progesterone levels that require
supplementation. Only a blood test or saliva test can tell you what your levels
actually look like.
At Women’s Health Network, we recommend having progesterone levels tested during
the mid-luteal stage of your menstrual cycle. Depending on the number of days in
your cycle, this usually occurs after ovulation, somewhere around day 21 of a classic
28–day cycle. Some practitioners provide a simple saliva test; others recommend
the more expensive blood test.
A typical finding in women of all ages during these tests is that “baseline” progesterone
levels are acceptable but the ratio of progesterone to estrogen is off. This doesn’t
mean your estrogen levels are abnormal (although, if you’re worried, you can test
your estrogen levels as well with a blood panel). Most of the time it simply means
the level of estrogen is out of sync with the progesterone level.
How does the ratio of estrogen to progesterone go awry? It may be that you are “estrogenic”
and your body readily converts progesterone into estrogen. Or you may be susceptible
— as many of us are — to the rising level of xenoestrogens and other endocrine disruptors
in our environment. These substances mimic estrogen in the body and can tip your
delicate hormonal balance. (You may also have other dietary or stress–related triggers
in addition to your hormones). Once you suspect that your headaches or migraines
have a hormonal component, you can do something about them.
Preventing hormonal headaches naturally
Getting to the root of these hormonal headaches means dealing with a temporary or
chronic imbalance of estrogen in relation to progesterone. A healthy diet that avoids
or eliminates simple carbohydrates, refined sugars, and processed foods is always
the first step. Our lifestyle
and nutritional guidelines can get you started.
The second step is to decrease or eliminate toxins that can be exacerbating your
hormonal imbalance. It’s always a good idea to be on the lookout for endocrine–disrupting
chemicals in your environment and avoid them as much as possible — even the perfume
in your cosmetics can trigger a migraine.
The third step is to fill in any dietary gaps with nutritional supplements. Good
choices to begin with are core nutrients like those offered in our Health Programs
— a rich multivitamin, essential fatty acids, and calcium/magnesium. Believe it
or not, all are crucial to supporting your hormone balance and restoring a good
progesterone-to-estrogen ratio. Additional nutritional measures include non-GMO
soy, fresh ground flax seed, or other foods high in fatty acids, fiber, and isoflavones
Specific supplements can nip migraines in the bud. Certain herbs have been used
to prevent and treat headaches by herbalists for thousands of years, with at least
two now solidly confirmed by scientists as effective in clinical trials: butterbur
(Petasites hybridus) and feverfew (Tanacetum parthenium). The
mineral magnesium and vitamin B2 (riboflavin) have both been demonstrated
to decrease migraine frequency in people who normally have multiple migraines a
month. By effective, I mean at least a 50% reduction in migraine frequency in some
Today there are various safe, over-the-counter migraine prevention formulas that
combine these natural ingredients, and I’d encourage you to look into them because
they can be especially helpful in combination formulas. For example, Migravent contains
all four of the above ingredients: feverfew, butterbur, magnesium, and riboflavin.
There are additional plant extracts and foods long used in various cultures to ameliorate
headaches and other symptoms associated with fluctuating hormones, including soy,
black cohosh (Cimicifuga racemosa) and dong quai (Angelica sinensis).
While I generally recommend that anyone considering the use of naturopathic remedies
consult the advice of a qualified practitioner, you can also talk to your regular
healthcare practitioner or call one of our Advisors. For many women, changes in
diet, nutrition level, and lifestyle are all they need to feel better.
Once you’ve established a basic core of nutrition, you may find that adding natural
hormone supplementation, specifically bioidentical progesterone at the right time
of the month, provides great relief. I recommend you work with a qualified healthcare
practitioner to explore the use of bioidentical hormone therapy. Here are some guidelines
from Women’s Health Network to discuss with your practitioner:
Using bioidentical hormones to abort hormonal headaches
For premenstrual and perimenopausal headaches and migraines
The most likely triggers for headaches that occur premenstrually, or those in perimenopause,
include a sensitivity to the natural drop-off in progesterone levels as the luteal
phase of your cycle (second half) progresses, or alternatively, an ongoing progesterone
deficit. For this pattern we recommend you apply the hormone cream as directed during
the last two weeks of your cycle.
Headaches and migraines during your period
If menstrual headaches persist throughout your period even after you’ve tried the
natural balancing measures, it may be helpful to try prescription low dose bioidentical
estrogen supplementation, such as the estradiol patch, during your period. Talk
to your healthcare practitioner about this.
A word about hormone use and hormonal headaches
While we believe that natural (bioidentical) hormone supplementation is an important
therapeutic for some women, and can be particularly useful in treating hormonal
headaches, hormones — even if they are natural — are very powerful. That’s why we
recommend a blood test for any woman who is interested in using hormones, especially
if she is nearing menopause. We think of any kind of hormonal supplementation as
a bridge to natural, self-sustaining hormonal balance, not an end solution.
If you are still menstruating or within a year of menopause, you may want to discuss
a trial of low-dose bioidentical progesterone, as described above, with your healthcare
provider. In combination with other lifestyle changes it may help your body become
more progesterone–balanced without further supplementation. For headache or migraine
relief, I do not suggest the use of synthetic progestins like Provera or synthetic
HRT combinations because they act more as vasoconstrictors and can actually worsen
headache symptoms. The pharmacokinetics of real, bioidentical progesterone are entirely
different as it is metabolized instinctively by the body.
Even with a low-dose, bioidentical hormone you should continue to exercise caution
and tune in to your body’s signals. If you are using bioidentical progesterone and
experience increased headache or other PMS symptoms such as breast tenderness, or
you begin to sense these symptoms at ovulation, you may be hard-wired to convert
extra progesterone into estrogen, in which case additional progesterone may not
be a good choice for you. With any persistent heavy bleeding, unusual spotting,
breast tenderness, or other serious symptoms while using bioidentical progesterone
products, discontinue use and contact your healthcare provider — further evaluation
may be needed.
Rescue treatments for hormonal headache pain
Becoming aware of the timing of your hormonal headaches or migraines can certainly
help you decrease their frequency with preventive measures, and I encourage you
to read our article on
chronic headaches, particularly the section on migraines, to learn more
about migraine patterns and theories. Nevertheless, even women who adopt the healthiest
lifestyle and dietary habits and hormonal–balancing measures can get the occasional
painful migraine. Life is full of stressors and you can’t be on top of all of them
all the time. When hormonal headaches and migraines arise acutely despite your best
efforts, prompt use of rescue treatment as early as possible will deliver the most
There are a few rescue meds to have in your medicine chest but use these with caution.
Take only as directed, and never use any drug without discussing your lifestyle
and other prescriptions with your practitioner first.
NSAIDs. Nonsteroidal anti-inflammatories (NSAIDs) can be particularly
helpful if used early and at your optimal dose. I suggest ibuprofen (brand names
Advil or Motrin) with food, up to 800 mg every 8 hours, no more than two days in
any given week (max is 2400 mg per 24-hour period). However, some women really respond
well to plain old-fashioned aspirin, and some swear by Excedrin Migraine, which
contains acetaminophen, aspirin, and caffeine.
If you are in the habit of taking NSAIDs, please read the section of our chronic
headache article on avoiding
rebound headaches. If you are trying to conceive or are pregnant, acetaminophen
(aka paracetamol, or brand name Tylenol) is the only recommended choice in the NSAID
category. Ibuprofen and aspirin can cause birth defects and other serious problems,
so be sure to discuss it with your midwife or obstetrician before using any medications.
Fortunately for hormonal headache sufferers, pregnancy is often a time of reprieve.
Triptans. These anti-migraine agents were once believed to work
by binding to serotonin receptors in the brain to constrict blood vessels and reduce
inflammation. This theory is being challenged and although it remains unclear how
the triptans work, this treatment can help some women. Some headache experts suggest
that women who observe that their migraines or debilitating headaches occur predictably
on certain days, e.g., day 1 or 2 of menses, take a triptan once or twice a day
on those days as prophylaxis. Although this usage has not been formally approved
by the FDA, you can ask your headache specialist about this option.
Imitrex, a popular brand of triptan, and others are pain formulations with long-acting
effect. Again, they work best when taken as close to the migraine onset (prodrome)
as possible. If one triptan doesn’t work well for you or you had side effects, another
formula may be better — so don’t despair, and try another one. We’re all different
with individual responses and it may just take time to figure out the right solution
for you. Triptans are not advisable for use in pregnancy, and must be used with
caution if you’re also on an SSRI antidepressant. Triptans come in pills, orally-disintegrating
tablets, nasal sprays, subcutaneous injections, and transdermal compressed medication
Other prescription migraine treatments. For a complete list of
migraine treatments used in conventional clinical settings, visit the website of
the National Headache Foundation.
Many of these treatments were developed to address other medical conditions, such
as heart disease, high blood pressure, depression, congestion, etc., but were coincidentally
found to help prevent the acute pain of migraines Although these treatments can
be effective, they can take about a month to kick in and need to be taken every
day in order to work. All of these drugs must be taken under strict medical supervision.
If you are currently taking any of these medications, it is still safe to consider
all of the other natural measures we’ve discussed above.
As headaches have so many potential contributing factors, I also suggest you review
our list of
ten ways to eliminate chronic headaches naturally. Implementing these practices,
too, will certainly help with hormonally-driven headaches and migraines. Hopefully,
with time, you will find yourself relying less and less on heavy-duty pain-relievers
and more on your body’s innate mechanisms for staying balanced and healthy.
Balanced and pain-free
While headaches may seem to be “all in your head,” the most effective treatment
for any health problem takes into account the needs of your whole body. Unlike conventional
medicine which only treats the pain, an integrative approach restores the baseline
ratio of hormones. If you and your practitioner think hormones are causing your
headaches, it may actually be good because it means that you have the opportunity
to take effective proactive measures.
By focusing on nutrition, proper supplements, and a healthy lifestyle, with careful
use natural hormonal support when needed, you can decrease both the frequency and
intensity of your hormonal headaches. You may even find that other symptoms dissipate
as well. This approach may require a few months for full results, but once you get
there, you may find your are completely free of headaches!
NOTE: Severe, blinding pain that comes on suddenly with no prior
migraine history should be taken seriously. If you are experiencing new or different
headaches, severe headaches, or headaches with associated sensory or neurological
symptoms, seek immediate help at your local hospital’s emergency department. DO
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