For those who like to understand the biology underlying
body processes like inflammation, here’s
a brief description of three major pro-inflammatory hormone groups and their fundamental
Prostaglandins are compounds found within most tissues
and organs that stimulate nerve cells, signalling pain to the brain and forcing
you to stop what you’re doing — “Drop the hot pan!” They
swell the blood vessels at the injured site, opening space in the capillary walls
for the white blood cells to enter. The blood and plasma rushing out of those enlarged
vessels causes the swelling, tenderness, and redness. Prostaglandins also cause
constriction as well as dilation of smooth muscle cells, and are responsible for
the pain of menstrual cramps.
Cytokines are immune system modulators produced by cells
throughout the body. Cytokines communicate with your brain, sounding the alarm when
they detect an intruder. A subclass of cytokines called leukotrienes (or interleukins)
ensures that the immune response is checked before it destroys outlying healthy
cells and tissue. Importantly, they call off the inflammatory response. If you have
overactive leukotrienes, your body can lose control of the process — white
blood cells begin to digest healthy tissue, causing excessive damage and scarring,
a common symptom in many autoimmune disorders.
Histamines are the chemicals responsible for the itchy
nose, watery eyes, or rash that often accompany an
allergic reaction. Their job is to help you rid yourself of whatever toxin
is causing the problem (by sneezing, coughing, crying, and scratching). They bring
more blood and lymphatic fluid to the site of the invasion, which transport your
white blood cells to the site and toxins away from it. The amount of histamine that
gets released determines how intense the allergy response will be.
In many of us, this delicate interplay of hormones is easily disrupted, leading
to chronic inflammation
that can wreak havoc on our health.
Relieve your hormonal
imbalance symptoms today