A mammogram is a 2-dimensional imaging tool that uses
x-rays to detect breast cancer in women without symptoms. Most women get what’s
known as screening mammograms. These imaging tests allow a radiologist the opportunity
to detect something new or see changes in your breast tissue.
guidelines do change and these updates can sometimes be difficult to sort out. There
were long-standing recommendations that women get mammograms once a year starting
at 40 and check their breasts monthly. But now the US Preventive Services Task Force,
or USPSTF, recommends that most women put off their first mammograms until age 50,
and then get them every other year instead of annually.
Early detection is the goal of mammograms
There is no one simple message when it comes to when and whether to have a mammogram.
Having annual mammograms will not prevent you from getting breast cancer. Mammography
will detect some pre-existing lumps, but the technology and the experience are far
from perfect. And mammograms do come with some real risks.
Eye on the world: Switzerland’s recommendations for mammograms
The Swiss Medical Board released a report in February of 2014 stating that evidence
does not support the conventional thinking that mammograms are safe and capable
of saving lives. The Board advised that women should be informed in a ‘balanced’
way, about the benefits and harms of screening.
The Swiss Medical Board recommends abolishing mammography as a mass-screening program
due to evidence of harm and the lack of benefit.
Though early detection through mammography is still the most widely available tool
we have to fight breast cancer, especially for women at elevated risk, mammography
is just one piece of the story. In terms of preventing breast cancer, a lot of research
points to the benefits of daily exercise, maintaining a healthy weight, eating soy,
and supplementing with fish oil, iodine, and indole-3-carbinol, a compound found
in cruciferous vegetables like broccoli.
Current guidelines for mammograms
The USPSTF now recommends that unless women have specific risk factors, they should
start mammography screening at age 50 and obtain a mammogram every two years, rather
than yearly. Over the past 30 years, mammograms have been shown to decrease breast
cancer deaths in women over 50 years of age by 30% but a benefit for women in their
40s was never clearly demonstrated.
The Task Force also recommends women discontinue screening mammograms at age 74.
Researchers found that not only did the great majority of women gain no benefit
from yearly screening mammograms, some are harmed. Other studies have pointed to
over-diagnosis and the emotional toll of false-positives as drawbacks to yearly
The American Cancer Society (ACS) now advises women with “average risk” to have
their first mammograms at age 45, instead of 40. But other groups, including the
American College of Radiology and the Society of Breast Imaging continue to recommend
annual mammograms starting at 40. The ACS also suggests that women with average
risk who are 55 and older should have mammograms every other year.
The USPSTF recommendations are based on:
- New statistical data from computerized models and a number of well-designed, carefully
conducted studies, each with over 10 years of follow-up, that showed mammogram screening
exams would prevent only 1 death in nearly 2000 women aged 40-49, with potentially
99 false-positive results per 1000 screening exams.
- The hazards from radiation exposure from extra images that cause added harm to this
- The studies and statistical analyses that showed no difference in survival among
women 50-69 years of age who were screened every 1 to 2 years.
False positive: A result that is incorrectly positive when a situation
is in fact normal.
False negative: A result that appears negative when in reality
there is an issue to investigate or treat.
These recommendations bring the US in line with the protocols followed by most European
countries for the last 10 years. Most of Europe does not have higher rates of death
from breast cancer than the US.
In another study reported in 2005 in the Journal of the National Cancer Institute,
researchers looked back at almost 4000 women in the US between the ages of 40 and
69. It was a surprise when the study found that women who underwent regular screening
died at the same rate as those who declined mammograms.
The results suggested there may be a benefit to regular screening for women who
are at increased risk for breast cancer due to family history or prior atypical
breast biopsy. (See the NCI’s free, interactive Breast Cancer Risk Assessment Tool and be sure to discuss
the results with your healthcare provider.)
Is there a “safe” choice when it comes to mammograms?
We all have known someone who has been diagnosed with the disease, or who has died
from breast cancer at a young age. Most women are willing to undergo whatever testing
is available if they think it will help them beat this frightening disease.
Even so we’re hearing more and more women ask, “Do I really need that mammogram?”
Breast health tips from Women's Health Network — there’s a lot you can do!
We still don’t know what causes breast cancer or exactly how to prevent it. But
there is great research out there on preventive measures to keep your breasts healthy.
- If you smoke, stop as soon as you can, and drink alcohol in moderation or not at
- Eat well, including lots of fresh fruits and vegetables (especially Brassica vegetables,
which contain indole-3-carbinol like broccoli, cabbage, cauliflower, turnips, kale,
kohlrabi), healthy fats, and lean protein, including soy.
- Take a daily
high-quality multivitamin that contains iodine and selenium, plus an
- Exercise 30-60 minutes 4 times per week, keep your
body mass index within a healthy range, and cultivate ways to decrease stress.
And there are some downsides to the test:
- Mammograms are uncomfortable and sometimes outright
- Mammograms come with high levels of false positives for younger women. An estimated
10% of mammograms are read as false positives, depending on the age of the woman,
the center, the radiologist, the equipment, and the protocol used to read the images.
This leads to increased anxiety and fear in many women.
- Mammograms can lead to unnecessary procedures. Mammograms lead to the diagnosis
of more cancers, but particularly in situ (confined to the original site) cancers,
which are generally noninvasive and not associated with an increase in mortality.
Are they actually saving lives? Perhaps not as many as you may hope. And many women
have unnecessary additional radiation and invasive surgical procedures.
- Mammograms expose you to radiation. There’s a risk-to-benefit ratio to consider,
and the younger we are when exposed to radiation, the more sensitive our tissues
are to it. Epidemiologists have calculated that cumulative radiation exposure from
yearly screening mammograms starting at 40 could cause a net overall increase in
- Up to 30% of cancers are missed. Many women may have had a false sense of security
after being told that their mammogram was normal only to be shocked to
find a lump a couple months later that turns out to be malignant.
Originally healthcare practitioners thought mammograms would help with early detection
of all breast cancer, but we now know that there are more than five types of breast
cancer. Some grow fast and act aggressively in the body, while others are slow growing.
Some types act in ways that make finding them early very helpful, while others do
not. And now we know that some forms of cancer might be better off left undetected
All of this information makes it important for women to discuss mammograms with
a trusted healthcare provider to balance risks and benefits with their own health
history and beliefs.
Mammography’s imaging limitations
It’s hard to get a quality image of the breast, otherwise known as what author Malcolm
Gladwell calls the “picture problem.” In the 2-D world of screening mammography,
two black-and-white pictures of each breast are taken. These contrasting views provide
some dimension, but not much.
Compression imaging was introduced in the early 1980s, which simplified the mammography
process and provided a better view — opening the door to mass screenings. While
the radiation doses have decreased significantly since the 1960s, not much else
has changed in terms of depth and detail in an average mammogram image.
What can a mammogram see?
Mammograms are clearest when imaging “fatty” breasts, which are naturally more prevalent
in older women — usually post-menopausal women not on HRT. Higher hormone levels
naturally cause breasts to be more fibrous and harder to image on a mammogram —
or “dense.” (Perhaps this is the reason mammograms are more beneficial for older
women). How your breasts feel to you does not always correlate with how they look
A textbook cancer — one that a medical student could see — would show up on a mammogram
as an irregular white shape, often called a mass or a nodule. “Nodule” refers to
lymph nodes, the little shapes generally seen higher up in the armpit. The white
shape shows up best on a background that is gray or black on a mammogram.
Dense breasts contain a lot of perfectly normal fibroglandular tissue that shows
up as white areas on a mammogram. Part of the image problem with mammograms of dense
breasts is that the white areas created by those fibrous tissues can conceal a small
cancer — like trying to find a polar bear in a snowstorm.
It’s best when women with family histories or other high-risk factors are screened
at a breast center where they’re informed of their results quickly and, if necessary,
additional imaging carried out right away. If not women should be scheduled right
away for follow-up, so the period of waiting without knowing is minimized. If you’re
in such a position, you can certainly advocate for having that experience.
There’s a lot of variation in how mammograms are read and human and technological
errors aren’t uncommon. That’s why it’s a good idea to get a second opinion whenever
there’s a questionable result.
Are there alternatives to mammography?
There are other forms of breast imaging in use and in development today that provide
an alternative picture of breast tissue. Some of these imaging techniques are still
experimental, some have limited availability, and some are considered more appropriate
for diagnostic rather than screening purposes. But you may be able to request an
alternative, if your breasts are dense, or you’re otherwise at higher risk, or you
do not believe in or want to have mammography.
Sometimes ultrasound screening or magnetic resonance imaging (MRI) of the breasts
is recommended as a follow-up to screening mammography. Because these techniques
are generally more costly, not all centers provide them and not all insurance policies
cover them. Ask your healthcare provider to discuss all your options — and verify
your insurance coverage beforehand so you know what to expect.
Many institutions have converted to digital rather than film mammography, where
the images are digitized. They can be reviewed on a high-resolution monitor and
the contrast and some other image qualities can be manipulated. Computer programs
have been developed to help analyze tissue changes that take place over time.
Some alternatives to traditional mammography
- Digital mammography
- MRI scan
Digital mammography offers significant benefits over film for premenopausal women
and women with dense breasts, according to a study published in NEJM. A radiologist
can view your files from a remote location which is helpful for second opinions.
False positives and false negatives are still possible, and digital mammography
is still not widely available in some areas.
Thermography, or heat detection, is an old method that newer technology is bringing
back. At this point, very few large studies have looked at thermography. We encourage
women interested in the test to find an experienced institution that will correlate
their findings with other testing. It's possible to see false positive and false
negative results with different practitioners using different types of cameras.
What is the bottom line on mammograms?
Mammography is definitely not as good as anyone wanted it to be — yet, anyway —
or as beneficial as we’d like it to be. Mostly, we think we are better off with
it than we would be without it. It may be prudent to follow the new guidelines and
get a mammogram every other year between the ages of 50 and 74, but it should always
be your choice. If you have good reasons not to get regular mammograms, your likelihood
of dying from breast cancer is still very small.
What you should take into account is your own individual health picture: your risk
factors, age, breast density, and your threshold for anxiety and risk. Some women
may be comfortable getting a mammogram only a couple times in their 40s and 50s;
others may want more regularly imaging.
Researchers are now studying markers of cancer (or risk of getting it) in
nipple aspirate fluid, blood, saliva and urine. Women will benefit if the
focus shifts to finding the cause or causes of breast cancer so we can learn how
to prevent it altogether.
Check out the Army of Women
for more information.
Mandelblatt, J., et al. 2009. Effects of mammography screening under different screening
schedules: Model estimates of potential benefits and harms. Ann. Int. Med., 151
(10), 738—747. URL: http://www.annals.org/content/151/10/738.full (accessed 11.17.2009).
Nelson, H., et al. 2009. Screening for breast cancer: An update for the US Preventive
Services Task Force. Ann. Intern. Med., 151 (1), 727—737, W237—W242. URL: http://www.annals.org/content/151/10/727.long
Stefanek, M., et al. 2010. Mammography and women under 50: Déjà vu all over again?
Cancer Epidemiol. Biomarkers Prev., 19 (3), 639. URL (paid access only): http://cebp.aacrjournals.org/content/19/3/635.long
Morrell, S., et al. 2009. Estimates of overdiagnosis of invasive breast cancer associated
with screening mammography. Cancer Causes Control. [Epub ahead of print.] URL: http://www.ncbi.nlm.nih.gov/pubmed/19894130
Gøtzsche, P., & Nielsen, M. 2009. Screening for breast cancer with mammography.
Cochrane Database Syst. Rev. (4), CD001877. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/19879455