Take an EXTRA 30% OFF any initial
Program purchase — limited time only!

Shop our products & programs

• Doctor-formulated
• Natural & effective
• 100% guaranteed
• Made in FDA-inspected labs



Arginelle acts as an aphrodisiac — helping to increase your libido, no matter what your age. Created specifically for women, our natural formula will help enhance your sexual desire, as well as promote your body’s sexual arousal response. Arginelle includes L-Arginine, which research shows increases sensation and responsiveness to stimulation, plus a wide range of other nutrients to support an increase in your sexual desire and pleasure.

Arginelle contains:

  • L-Arginine — this amino acid supports nitric oxide synthesis, resulting in blood vessel relaxation, supporting vaginal blood flow, sensation and responsiveness to stimulation.
  • Choline — an essential nutrient related to B-complex vitamins. It is a precursor to acetylcholine, supporting vaginal blood flow and smooth muscle contractions.
  • Eleuthero (Siberian ginseng) — an adaptogenic herb used for centuries in Asia to increase endurance, immune function and overall well-being. Also traditionally used for strengthening and increasing stamina.
  • B vitamins — including thiamin, riboflavin, niacin, vitamin B6 and panthotenic acid to support an increase in energy.
  • Muira puama — used by indigenous peoples as an aphrodisiac and to increase sexual vitality. Also known as “potency wood.”
  • Tribulus — utilized in ancient Greece and India to support physical rejuvenation. Also used in Eastern European folk medicine for increased strength and sexual potency.
  • Ginkgo — drawn on medicinally for thousands of years to support sexual performance.
  • Damiana — used in traditional medicine of Africa and Central and South America as an aphrodisiac.
  • Shilajit — widely used in Ayurvedic medicine, this mineral-rich natural substance is believed to enhance sexual activity.
  • Maca — used for more than 2,000 years as an aphrodisiac and for stress relief.

Our Arginelle is:

  • Formulated specifically for women.
  • Safe & natural.
  • Based on the latest medical research.
  • Made from the highest quality ingredients without yeast, wheat, soy protein, milk/dairy, corn, sugar, starch, or artificial colors, preservatives or flavors.
  • Laboratory-assayed to ensure purity and quality – the same rigorous procedure that is used for pharmaceutical drugs.
  • Made in a facility validated by NSF International to meet or exceed all governmental requirements for Good Manufacturing Practices (the FDA's GMP's).

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Arginelle Ingredients

Product References

Arginelle is doctor-formulated to be complete, natural, bioavailable, and manufactured to pharmaceutical standards.

The following articles, arranged in order of recency, represent a sampling of the research on the constituents of Arginelle.

B Vitamins (Thiamin, Riboflavin, Niacin, Vitamin B6, Pantothenic Acid)

Bailey, L.. & Gregory, J. 1999. Folate metabolism and requirements. J. Nutr., 129, 779–782.

Ball, G. 2006. Chapter 11: Pantothenic Acid. In Vitamins in Foods: Analysis, Bioavailability, and Stability, 211–219. Boca Raton, FL: CRC Press.

Baez–Saldana, A., et al. 2004. Effects of biotin on pyruvate carboxylase, acetyl-CoA carboxylase, propionyl-CoA carboxylase, and markers for glucose and lipid homeostasis in type 2 diabetic patients and nondiabetic subjects. Am. J. Clin. Nutr., 79, 238–243.

Baily, S. E. and Ayling, J. E. 2009. The extremely slow and variable activity of dihydrofolate reductase in human liver and its implications for high folic acid intake. Proc Natl Acad Sci USA., 106(35): 15424-15429. doi: 10.1073/pnas.0902072106. URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730961/?tool=pubmed (accessed 5/14/2012).

Baker, H., et al. 1975. Inability of chronic alcoholics with liver disease to use food as a source of folates, thiamin and vitamin B6. Am. J. Clin. Nutr., 28, 1377–1380.

Bart, S. Sr., et al. 2012. Folate status and homocysteine levels during a 24-week oral administration of folate-containign oral contraceptive: a randomized, double-blind, active-controlled, parallel-group, US-based multicenter study. Contraception. 85(1): 42-50. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/22067790 (accessed 5/15/2012).

Batra, V., et al. 2010. Enhanced one-carbon flux towards DNA methylation: Effect of dietary methyl supplements against gamma-radiation-induced epigenetic modicationas. Chem Biol Interac., 183(3): 425-33. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/19931232 (Accessed 5/15/2012).

Bird, L. M., et al. 2011. A therapeutic trial of pro-methylation dietary supplements in Angelman syndrome. Am J Med Genet A., 155A(12): 2956-63. doi: 10.1002/ajmg.a.34297. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/22002941 (accessed 5/14/2012).

Cagnacci, A., et al. 2009. High-dose short-term folate administration modifies ambulatory blood pressure in postmenopausal women. A placebo-controlled study. Eur J Clin Nutr. 63(10): 1266-8. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/19603054 (accessed 5/14/2012).

Chang, N., et al. 2001. Study of the relation between proton magnetic resonance spectroscopy metabolites in the brain regions and the B vitamin status in alcoholics. Nutr. Res., 21, 811–820.

Clarke, R. 2006. Vitamin B12, folic acid, and the prevention of dementia. NEJM, 354, 2817–2819.

Colombo, V., et al. 1990. Treatment of brittle fingernails and onychoschizia with biotin: Scanning electron microscopy. J. Am. Acad. Dermatol., 23, 1127–1132.

Combs, G., 1992. Vitamin B6 (Chapter 13), and Vitamin B12 (Chapter 17). In The Vitamins: Fundamental Aspects in Nutrition and Health, 331–347; 403–419. San Diego: Academic Press.

Coppen, A., & Bailey, J. 2000. Enhancement of the antidepressant action of fluoxetine by folic acid: A randomised, placebo controlled trial. J. Affect. Disord., 60, 121–130.

Coppen, A., & Bolander-Gouaille, C. 2005. Treatment of depression: Time to consider folic acid and vitamin B12. J. Psychopharm., 19, 59–65.

Crawford, V., et al. 1999. Effects of niacin-bound chromium supplementation on body composition in overweight African-American women. Diab. Obes. Metabol., 1, 331–337.

Cravo, M., et al. 1996. Hyperhomocysteinemia in chronic alcoholism: Correlation with folate, vitamin B-12, and vitamin B-6 status. Am. J. Clin. Nutr., 63, 220–224.

Davis, B., et al. 1982. Enhanced absorption of oral vitamin B12 from a resin ascorbate administered to normal subjects. Manip. Physiol. Ter., 5, 123–127.

Duan, W., et al. 2002. Dietary folate deficiency and elevated homocysteine levels endanger dopaminergic neurons in models of Parkinson’s disease. J. Neurochem., 80, 101–110.

Eussen, S., et al. 2005. Oral cyanocobalamin supplementation in older people with vitamin B12 deficiency: A dosefinding trial. Arch. Intern. Med., 165, 1167–1172.

Fava, M., and Mischoulon, D. 2009. Folate in depression: efficacy, safety, differences in formulations, and clinical issues. J Clin Psychiatry. 70 Supple 5: 12-7. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/19909688 (accessed 5/14/2012).

Floersheim, G. 1989. [Treatment of brittle fingernails with biotin]. Z. Hautkr., 64, 41–48.

Geohas, J., et al. 2007. Chromium picolinate and biotin combination reduces atherogenic index of plasma in patients with type 2 diabetes mellitus: A placebo-controlled, double-blinded, randomized clinical trial. Am. J. Med. Sci., 333, 145–153.

Godfrey, P. S., et al. 1990. Enhancement of recovery from psychiatric illness by methylfolate. Lancet, 336(8712): 392-5. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/1974941 (accessed 5/14/2012).

Greenberg, J. A., and Bell, S. J. 2011. Multivitamin Supplementation During Pregnancy: Emphasis on Folic Acid and L-Methylfolate. Rev Obstet Gynecol., 4 (3-4): 126-7. URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250974/?tool=pubmed (accessed 5/14/2012).

Hassing, L., et al. 1999. Further evidence on the effects of vitamin B12 and folate levels on episodic memory functioning: A population-based study of healthy very old adults. Biol. Psych., 45, 1472–1480.

Hintikka, J., et al. 2003. High vitamin B12 level and good treatment outcome may be associated in major depressive disorder. BMC Psych., 3, 17.

Hochman, L., et al. 1993. Brittle nails: Response to daily biotin supplementation. Cutis, 51, 303–305

Kelly, P., et al. 1997. Unmetabolized folic acid in serum: acute studies in subjects consuming fortified food and supplements. Am J Clin Nutr., 65(6): 1790-5. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/9174474 (accessed 5/14/2012).

Koutsikos, D., et al. 1990. Biotin for diabetic peripheral neuropathy. Biomed. Pharmacother., 44, 511–514.

Lamers, Y., et al. 2006. Red blood cell folate concentrations increase more after supplementation with [6S]-5-methyltetrahydrofolate than with folic acid in women of childbearing age. Am J Clin Nutr. 84(1): 156-61.

Lee, B., et al. 2004. Folic acid and vitamin B12 are more effective than vitamin B6 in lowering fasting plasma homocysteine concentration in patients with coronary artery disease. Eur. J. Clin. Nutr., 58, 481–487.

Levine, S., & Saltzman, A. 2004. Pyridoxine (vitamin B6) neurotoxicity: Enhancement by protein-deficient diet. J. Appl. Toxicol., 24, 497–500.

Lewerin, C., et al. 2003. Reduction of plasma homocysteine and serum methylmalonate concentrations in apparently healthy elderly subjects after treatment with folic acid, vitamin B12 and vitamin B6: A randomised trial. Eur. J. Clin. Nutr., 57, 1426–1436.

Maas, A., et al. 1998. Riboflavin and vitamin B-6 intakes and status and biochemical response to riboflavin supplementation in free-living elderly people. Am. J. Clin. Nutr. 68, 389–395.

Masse, P., et al. 1998. A cartilage matrix deficiency experimentally induced by vitamin B6 deficiency. Proc. Soc. Exp. Biol. Med., 217, 97–103.

Masse, P., et al. 1990. Morphological abnormalities in vitamin B6 deficient tarsometatarsal chick cartilage. Scanning Microsc., 4, 667–673; discussion 674.

Masse, P., et al. 1994. Vitamin B6 deficiency experimentally-induced bone and joint disorder: Microscopic, radiographic and biochemical evidence. Br. J. Nutr., 71: 919–932.

McCormick, D. 1975. Biotin. Nutr. Rev., 33, 97–102.

Meshkin, B., Blum, K. 2007. Folate nutrigenetics: a convergence of dietary folate metabolism, folic acid supplementation, and folate antagonist pharmacogenetics. Drug Metab Lett., 1(1): 55-60. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/19356019 (accessed 5/14/2012).

Miller, J. 2004. Folate, cognition, and depression in the era of folic acid fortification. J. Food Sci., 69, 61–64.

Misir, R., & Blair, R. 1986. Effect of biotin supplementation of a barley-wheat diet on restoration of healthy feet, legs and skin of biotin deficient sows. Res. Vet. Sci., 40, 212-218.

Mock, D., et al. 2002. Marginal biotin deficiency during normal pregnancy. Am. J. Clin. Nutr., 75, 295–299.

Mock, D. 1991. Skin manifestations of biotin deficiency. Semin. Dermatol., 10, 296-302.

Morris, M. 2002. Folate, homocysteine, and neurological function. Nutr. Clin. Care, 5, 124–132.

Nyhan, W. 1987. Inborn errors of biotin metabolism. Arch. Dermatol., 123, 1696–1698a.

Pietrzik, K., et al. 2010. Folic acid and L-5-methyltetrahydrofolate: comparison of clinical pharmacokinetics and pharmacodynamics. Clin Pharmacokinet., 49(8): 535-48. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/20608755 (accessed 5/14/2012).

Preuss, H., et al. 2000. Effects of niacin-bound chromium and grape seed proanthocyanidin extract on the lipid profile of hypercholesterolemic subjects: A pilot study. J. Med., 31, 227–246.

Rampersaud, G., et al. 2003. Folate: A key to optimizing health and reducing disease risk in the elderly. J. Am. Coll. Nutr., 22, 1–8.

Revilla–Monsalve, C., et al. 2006. Biotin supplementation reduces plasma triacylglycerol and VLDL in type 2 diabetic patients and in nondiabetic subjects with hypertriglyceridemia. Biomed. Pharmacother., 60, 182–185.

Reynolds, T., et al. 1992. Hip fracture patients may be vitamin B6 deficient. Controlled study of serum pyridoxal-5’-phosphate. Acta Orthop. Scand., 63, 635–638.

Riggs, K., et al. 1996. Relations of vitamin B-12, vitamin B-6, folate, and homocysteine to cognitive performance in the Normative Aging Study. Am. J. Clin. Nutr., 63, 306–314.

Scambi, C., et al. 2009. Preliminary evidence for cell membrane amelioration in children with cystic fibrosis by 5-MTHF and vitamin B12 supplementation: a single arm trial. PLoS One. 4(3):e4782. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/19277125 (accessed 5/15/2012).

Sharp, L., Little, J. 2004. Polymorphisms in genes involved in folate metabolism and colorectal neoplasia: a HuGE review. Am J Epidemiol., 159(5): 423-43. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/14977639 (accessed 5/14/2012).

Stabler, S., & Allen, R. 2004. Vitamin B12 deficiency as a worldwide problem. Annu. Rev. Nutr., 24, 299–326.

Van Guelpen, B., et al. 2005. Folate, vitamin B12, and risk of ischemic and hemorrhagic stroke: A prospective, nested case-referent study of plasma concentrations and dietary intake. Stroke, 36, 1426–1431.

Zempleni, J., & Mock, D. 2000. Marginal biotin deficiency is teratogenic. Proc. Soc. Exp. Biol. Med., 223, 14–21.

Zempleni, J., & Mock, D. 1999. Bioavailability of biotin given orally to humans in pharmacologic doses. Am. J. Clin. Nutr., 69, 504–508.

Zhang, H., et al. 1997. Biotin administration improves the impaired glucose tolerance of streptozotocin-induced diabetic Wistar rats. J. Nutr. Sci. Vitaminol. (Tokyo), 43, 271-280.


Basha, M., et al. 2009. Functional significance of muscarinic receptor expression within the proximal and distal rat vagina. Am J Physiol Regul Integr Comp Physiol. 297(5): R1486-R1493. URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777769/ (accessed 8/29/2013).

Buchman, A.L., et al. 2001. Choline deficiency causes reversible hepatic abnormalities in patients receiving parenteral butrition: proof of a human choline requirement: a placebo-controlled trial. JPEN J Parenter Enteral Nutr. 25(5): 260-8. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/11531217?dopt=Abstract (accessed 8/29/2013).

Deuster, P.A., et al. 2002. Choline ingestion does not modify physical or cognitive performance. Mil Med. 167 (12): 1020-5. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/12502178?dopt=Abstract (accessed 8/29/2013).

Guerrerio, A.L., et al. 2011. Oral choline supplementation in children with intestinal failure. J Pediatr Gastroenterol Nutr. 53(1): 115-9. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/21694550 (accessed 10.29.2013).

Giuliano, F., et al. 2002. Neurophysiology and Pharmacology of Female Genital Sexual Response. Journal of Sex & Marital Therapy. 28:1 (101-121). URL (abstract): http://www.tandfonline.com/doi/abs/10.1080/00926230252851230#.Uh9mV13D8aU (accessed 8/29/2013).

Innis, S.M., et al. 2007. Choline-related supplements improve abnormal plasma methinine-homocysteine metabolites and glutathione status in children with cystic fibrosis. Am J Clin Nutr. 85(3): 702-8. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/17344490 (accessed 10.29.2013).

Jiang, X., et al. 2013. A higher maternal choline intake among third-trimester pregnant women lowers placental and circulating concentrations of the antiangiogenic factor fms-like tyrosine kinase-1 (sFLT1). FASEB J. 27(3): 1245-53. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/23195033 (accessed 10.29.2013).

Penry, J.T. & Manore, M.M. 2008. Choline: an important micronutrient for maximal endurance-exercise performance? Int J Sport Nutr Exerc Metab. 18(2): 191-203. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/18458362?dopt=Abstract (accessed 8/29/2013).

Ross, R.G., et al. 2013. Perinatal choline effects on neonatal pathophysiology relate to later schizophrenia risk. Am H Psychiatry. 170(3): 290-8. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/23318559 (accessed 10.29.2013).

Sidhu, N., et al. Oral choline supplementation for postoperative pain. Br. J Anaesth. 111(2):249-55. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/23568851 (accessed 10.29.2013).

Wallace, J.M., et al. 2012. Choline supplementation and measures of choline and betaine status: a randomized, controlled trail in postmenopausal women. Br J Nutr. 108(7): 1264-71. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/22172554 (accessed 10.29.2013).

West, A.A., et al. 2013. Choline intake influences phosphatidylcholine DHA enrichment in nonpregnat women but not in pregnant women in the third trimester. Am J Clin Nutr. 97(4): 718-27. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/23446897 (accessed 10.29.2013).

Zeisel, S.H. 2004. Nutritional importance of choline for brain development. J Am Coll Nutr. (6 Supple): 621S-626S. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/15640516?dopt=Abstract (accessed 8/29/2013).

Damiana (Turnera diffusa)

Alarcon-Aguilsar, F.J., et al. 2002. Investigation on the hypoglycaemic effects of extracts of four Mexican medicinal plants in normal and alloxan-diabetic mice. Phytother Res. 16(4): 383-6. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/12112298 (accessed 11.22.2013).

Anderson, T. & Fogh, J. 2001. Weight loss and delayed gastric emptying following a South American herbal preparation in overweight patients. J Hum Nutr Diet. 14(3): 243-50. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/11424516 (accessed 11.22.2013).

Bezzara, A.G., et al. 2013. Effects of Panax ginseng, Turnera diffusa and Heteropterys tomentosa extracts on hippocampal apoptosis of aged rats. Einstein (Sao Paulo). 11(2): 163-7. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/23843055/ (accessed 11.22.2013).

Estrada-Reyes, R., et al. 2009. Turnera diffusa Wild (Turneraceae) recovers sexual behavior in sexually exhausted males. J Ethnopharmacol. 123 (3): 423-9. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/19501274 (accessed 11.22.2013).

Harrold, J.A., et al. 2013. Acute effects of a herb extract formulation and inulin fibre on appetite, energy intake and food choice. Appetite. 62: 84-90. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/23207186 (accessed 11.22.2013).

Ito, T.Y., et al. 2006. The enhancement of female sexual function with ArginMax, a nutritional supplement, among women differing in menopausal status. J Sex Marital Ther. 32(5): 369-78. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/16959660 (accessed 11.22.2013).

Ido, T.Y., et al. 2001. A double-blind placebo-controlled study of ArginMax, a nutritional supplement for enhancement of female sexual function. J Sex Marital Ther. 27(5): 541-9. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/11554217 (accessed 11.22.2013).

Sarris, J., et al. 2013. Plant-based medicines for anxiety disorders, Part1: a review of preclinical studies. CNS Drugs. 27(3): 207-19. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/23436255 (accessed 11.22.2013).

Taha, M.M., et al. 2012. Gastroprotective activities of Turnera diffusa Willd. Ex Schult. Revisited: Role of arbutin. J Ethnopharmacol. 141(1): 273-81. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/22374081 (accessed 11.22.2013).

Torres-Gonzalez, L., et al. 2011. Protective effect of four Mexican plants against CCI4-induced damage on the Huh7 human hepatoma cell line. Ann Hepatol. 20(1): 73-9. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/21301013 (accessed 11.22.2013).

Yakoot, M., et al. 2011. Effectiveness of a herbal formula in women with menopausal syndrome. Forsch Komplementmed. 18(5): 264-8. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/22105039 (accessed 11.22.2013).


Eleutherococcus senticosus Monograph. Alternative Medicine Review. 11(2): 151-55. Thorne Research, Inc. URL: http://www.modernhealthshop.com/wp-content/uploads/2013/02/Eleutherococcus-senticosus.pdf?TB_iframe (accessed 10.30.2013).

Chen, T.S., et al. 2008. Antioxidant evaluation of three adaptogenic extracts. Am J Chin Med. 36(6): 1209-17. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/19051347 (accessed 10.30.2013).

Cicero, A.F., et al. 2004. Effects of Siberian ginseng (Eleutherococcus senticosus maxim.) on elderly quality of life: a randomized clinical trial. Arch Gerontol Geriatr Suppl. (9): 69-73. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/15207399 (accessed 11.21.2013).

Deyama, T., et al. 2001. Constituents and pharmacological effects of Eucommia and Siberian ginseg. Acta Pharmacol Sin. 22(12): 1057-70. URL: http://www.chinaphar.com/1671-4083/22/1057.pdf (accessed 11.07.2013).

Eschbach, L.F., et al. 2000. The effect of Siberian ginseng (Eleutherococcus senticosus) on substrate utilization and performance. Int J Sport Nutr Exerc Metab. 10(4): 444-51. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/11099371 (accessed 11.21.2013).

Gaffney, B.T., et al. 2001. Panax ginseng and eleutherococcus senticosus may exaggerate an already existing biphasic response to stress via inhibition of enzymes which limit the binding of stress hormones to their receptors. Med Hypotheses. 56(5): 567-72. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/11388770 (accessed 10.30.2013).

Gaffney, B.T., et al. 2001. The effects of Eleuthero senticosus and Panax ginseng on steroidal hormone indices of stress and lymphocyte subset numbers in endurance athletes. Life Sci. 70(4): 431-42. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/11798012 (accessed 10.31.2013).

Goulet, E.D. & Dionne, I.J. 2005. Assessment of the effects of eleutherococcus senticosus on endurance performance. Int J Sport Nutr Exerc Metab. 15(1): 75-83. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/15902991 (accessed 11.21.2013).

Huang, L., et al. 2011. Acanthopanax senticosus: review of botany, chemistry and pharmacology. Pharmazie. 66(2): 83-97. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/21434569 (accessed 11.07.2013).

Huang, L.Z., et al. 2011. Bioactivity-guided fractionation for anti-fatigue property of Acanthopanax senticosus. J Ethnopharmacol. 133(1): 213-9. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/20920564 (accessed 11.07.2013).

Hwang, Y.C., et al. 2009. The effects of Acanthopanax senticosus extract on bone turnover and bone mineral density in Korean postmenopausal women. J Bone Miner Metab. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/19452124 (accessed 10.31.2013).

Kimura, Y. & Sumiyoshi, M. 2004. Effects of various Eleutherococcus senticosus cortex on swimming time, natural killer activity and corticosterone level in forced swimming stressed mice. J Ethnopharmacol. 95(2-3): 447-53. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/15507373 (accessed 10/31/2013).

Kuo, J., et al. 2010. The effect of eight weeks of supplementation with Eleuthorococcus senticosus on endurance capacity and metabolism in human. Chin J Physiol. 53(2): 105-11. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/21793317 (accessed 10.30.2013).

Panossian, A. & Wikman, G. 2009. Evidence-based efficacy of adaptogens in fatigue, and molecular mechanisms related to their stress-protective activity. Curr Clin Pharmacol. 4(3): 198-219. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/19500070 (accessed 11.07.2013).

Schaffler, K., et al. 2013. No benefit adding eleutherococcus senticosus to stress management training in stress-related fatigue/weakness, impaired work or concentration, a randomized controlled study. Pharmacopsychiatry. 46(5): 181-90. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/23740477 (accessed 11.21.2013).

Sievenpiper JL, Arnason JT, Leiter LA, Vuksan V. Decreasing, null and increasing effects of eight popular types of ginseng on acute postprandial glycemic indices in healthy humans: the role of ginsenosides. J Am Coll Nutr. 2004 Jun;23(3):248-58. PubMed PMID: 15190050. URL (abstract) http://www.ncbi.nlm.nih.gov/m/pubmed/15190050/ (accessed 11.21.2013)

Smalinskiene, A., et al.

Cicero, A.F., et al. 2004. Effects of Siberian ginseng (Eleutherococcus senticosus maxim.) on elderly quality of life: a randomized clinical trial. Arch Gerontol Geriatr Suppl. 2004;(9):69-73. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/15207399 (accessed 11.14.2013).

Kwan, C.Y., et al. 2004. Vascular effects of Siberian ginseng (Eleutherococcus senticosus): endothelium-dependent NO- and EDHF-mediated relaxation depending on vessel size. Naunyn Schmiedebergs Arch Pharmacol. 2004 May;369(5):473-80. Epub 2004 Apr 17. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/15095033 (accessed 11.14.2013)

Fadzel Wong Chee Ping, et al. 2011. Effects of acute supplementation of Panax ginseng on endurance running in a hot & humid environment Indian J Med Res. 2011 January; 133(1): 96–102 URL (abstract): http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100154/ (accessed 11.14.2013)


Alizadeh, M., et al. 2012. Effect of L-arginine and selenium added to a hypocaloric diet enriched with legumes on cardiovascular disease risk factors in women with central obesity: a randomized, double-blind, placebo-controlled trial. Ann Nutr Metab. 60(2): 157-68. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/22517293 (accessed 9/03/2013).

Allahdadi, K.J. URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008577/ (accessed 8/30/2013).

Aung, H.H., et al. 2004. Alternative Therapies for Male and Female Sexual Dysfunction. Am J Chin Med. 32(2): 161-173. URL: http://li123-4.members.linode.com/files/Alternative%20Therapies%20for%20Male%20and%20Female%20Sexual%20Dysfunction.pdf (accessed 9/03/2013).

Beharry, R.K., et al. 2008. Restoration of female genital vasocongestive arousal responses in young and aged rats. J Sex Med. 5(4): 804-12. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/18221278 (accessed 9/03/2013).

Berman, J.R., et al. 1998. Effect of estrogen withdrawal on nitric oxide synthase expression and apoptosis in the rat vagina. Urology. 51(4): 650-6. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/9586624 (accessed 9/03/2013).

Berman, J.R., et al. 2000. Anatomy and physiology of female sexual function and dysfunction: classification, evaluation and treatment options. Eur Urol.38(1): 20-9. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/10859437 (accessed 9/03/2013)/

Berman, J.R. 2005. Physiology of female sexual function and dysfunction. Int J Impo Res. 17: S44-S51. URL: http://www.nature.com/ijir/journal/v17/n1s/full/3901428a.html (accessed 9/03/2013).

Bogdanski, P., et al. 2012. Effect of 3-month L-arginine supplementation on insulin resistance and tumor necrosis factor activity in patients with visceral obesity. Eur Rev Med Pharmacol Sci. 16(6): 816-23. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/22913215 (accessed 9/03/2013).

Burnett, A.L. et al. 1997. Immunohistochemical description of nitric oxide synthase isoforms in human clitoris. J Urol. 158(1): 75-8. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/?term=9186326 (accessed 9/03/2013).

Caruso, S., et al. 2001. Premenopausal women affected by sexual arousal disorder treated with sildenafil: a double-blind, cross-over, placebo-controlled study. BJOG. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/11426898 (accessed 9/03/2013).

Chilosi, A., et al. 2012. Neuropsychological profile and clinical effects of arginine treatment in children with creatine transport deficiency. Orphanet J Rare Dis. 7:43. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/22713831 (accessed 9/03/2013).

Gianfrilli, D., et al. 2012. Propionyl-L-carnitine, L-arginine and niacin in sexual medicine: a neutraceutical approach to erectile dysfunction. Andrologia. 44 Suppl 1:600-4. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/21966881 (accessed 8/30/2013).

Goldstein, I. & Berman, J.R. 1998. Vasculogenic female arousal dysfunction: vaginal engorgement and clitoral erective insufficiency syndromes. Int J Impot Res. 10 Suppl 2: S84-90. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/9647967 (accessed 9/03/2013).

Ito, T.Y., et al. 2001. A double-blind placebo-controlled study of ArginMax, a nutritional supplement for the enhancement of female sexual function. J Sex Marital Ther. 27(5): 541-9. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/11554217 (accessed 9/03/2013).

Ito, T.Y., et al. 2006. The enhancement of female sexual function with ArginMax, a nutritional supplement, among women differing in menopausal status. J Sex Marital Ther. 32(5): 369-78. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/16959660 (accessed 9/03/2013).

Jabecka, A., et al. 2012. Oral L-arginine supplementation in patients with mild arterial hypertension and its effect on plasma level of asymmetric dimethylarginine, L-citruline, L-arginine and antioxidant status. Eur Rev Med Pharmacol Sci. 16(12): 1665-74. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/23161038 (accessed 9/03/2013).

Kim, N.N., et al. 2004. Role of arginase in the male and female sexual arousal response. J Nutr. 134 (10 Supple): 2873S-2879S. URL: http://jn.nutrition.org/content/134/10/2873S.full (accessed 8/30/2013).

Laan, E., et al. 1995. Assessment of female sexual arousal: response specificity and construct validity. Psychophysiology. 32(5): 476-85. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/7568642 (accessed 9/03/2013).

Laan, E. & Everaerd, W. 1998. Physiological measure of vaginal vasocongestion. Int J Import Res. 10 Supple 2: S107-10. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/9647971 (accessed 9/03/2013).

Leventhal, J.L. 1999. Management of Libido Problems in Menopause. Presented at the Conjoint Annual Meeting of the American Society for Reproductive Medicine and the Canadian Fertility and Andrology 32nd Annual Postgraduate Program, Toronto, Canada, 9/25-26, 1999. URL: http://xnet.kp.org/permanentejournal/sum00pj/libido.html (accessed 9/03/2013).

McKay, D. 2004. Nutrients and botanicals for erectile dysfunction: examining the evidence. Altern Med Rev. 9(1): 4-16. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/15005641 (accessed 9/03/2013).

Meston, C.M. & Frohlich, P.F. 2000. The neurobiology of sexual function. Arch Gen Psychiatry. 57(11): 1012-30. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/11074867 (accessed 9/03/2013).

Meston, C.M. & Worcel, M. 2002. The effects of yohimbe plus L-arginine glutamate on sexual arousal and in postmenopausal women with sexual arousal disorder. Arch Sex Behav. 31(4): 323-32. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/12187545 (accessed 9/03/2013).

Monti, L.D., et al. 2012. Effect of long-term oral l-arginine supplementation on glucose metabolism: a randomized, double-blind, placebo-controlled trial. Diabetes Obes Metab. 14(10):893-900. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/22553931 (accessed 9/03/2013).

Ogungbemi, S.I., et al. 2013. L-arginine increase nitric oxide and attenuates pressor and heart rate responses to change in posture in sickle cell anemia subjects. Niger J Physiol Sci. 28(1): 45-50. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/23955406 (accessed 8/30/2013).

Park, K., et al. 1997. Vasculogenic female sexual dysfunction: the hemodynamic basis for vaginal engorgement insufficiency and clitoral erectile insufficiency. Int J Impot Res. 9(1): 27-37. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/9138056 (accessed 9/03/2013).

Park, K., et al. 1998. Sildenafil inhibits phosphodiesterase type 5 in human clitoral corpus cavernosum smooth muscle. Biochem Biophys Res Commun. 249(3):612-7. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/9731184 (accessed 9/03/2013).

Phillips, N. 2000. Female Sexual Dysfunction: Evaluation and Treatment. Am Fam Physician. 62(1): 127-136. URL: http://www.aafp.org/afp/2000/0701/p127.html (accessed 9/03/2013).

Polycarpou, E., et al. 2013. Oral L-arginine supplementation and faecal calprotectin levels in very low birth weight neonates. J Perinatol. 33(2): 141-6. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/22555780 (accessed 9/03/2013).

Ralph, A.P., et al. 2013. L-arginine and Vitamin D Adjunctive Therapies in Pulmonary Tuberculosis: A Randomised, Double-Blind, Placebo-Controlled Trial. PLoS One. 8(8):e70032. URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743888/ (accessed 8/30/2013).

Sarrel, P.M. 1998. Ovarian hormones and vaginal blood flow: using laser Doppler celocimetry to measure effects in a clinical trial of post-menopausal weomn. Int J Impot Res. 10 Suppl 2: S91-3. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/9647968 (accessed 9/03/2013).

Sydow, K., et al. 2003. ADMA and oxidative stress are responsible for endothelial dysfunction in hyperhomocyst(e) inemia: effects of L-arginine and B vitamins. Cardiovasc Res. 57(1): 244-52. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/12504835 (accessed 9/03/2013).

Wu, Z., et al. 2012. Regulation of brown adipose tissue development and white fat reduction by L-arginine. Curr Opin Clin Nutr Metab Care. 15(6): 529-38. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/23075933 (accessed 9/03/2013).


Balick, M.J. & Lee, R. 2002. Maca: from traditional food crop to energy and libido stimulant. Altern Ther Health Med. 8(2): 96-8. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/11890390 (accessed 9/09/2013).

Bogani, P., et al. Lepidium meyenii (Maca) does not exert direct androgenic activities. J Ethnopharmacol. 104(3): 415-7. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/16239088 (accessed 9/11/2013).

Brooks, N.A., et al. 2008. Beneficial effects of Lepidium meyenii (Maca) on psychological symptoms and measures of sexual dysfunction in postmenopausal women are not related to estrogen or androgen content. Menopause. 15(6): 1157-62. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/18784609 (accessed 9/11/2013).

Cicero, A.F., et al. 2001. Lepidium meyenii Walp. improves sexual behavior in male rats independently from its actions on spontaneous locomotor activity. J Ethnopharmacol. 75(2-3): 225-9. URL (abstract olyhttp://www.ncbi.nlm.nih.gov/pubmed/11297856 (accessed 9/11/2013).

Dording, C.M., et al. 2008. A double-blind, randomized, pilot dose-finding study of maca root (L. meyenii) for the management of SSRI-induced sexual dysfunction. CNS Neurosci Ther. 14(3): 182-90. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/18801111 (accessed 9/09/2013).

Gonzales, G.F., et al. 2003. Effect of Lepidium meyenii (Maca), a root with aphrodisiac and fertility-enhancing properties, on serum reproductive hormone levels in adult healthy men. J Endocrinol. 176(1): 163-8. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/12525260 (accessed 9/11/2013).

Gonzales, G.F. 2012. Ethnobiology and Ethnopharacology of Lepidium meyenii (Maca), a Plant from the Peruvian Andes. Evid Based Complement Alternat Med. 2012: 193496. URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184420/ (accessed 9/11/2013).

Gonzales, G.F., et al. 2013. Role of Maca (Lepidium meyenii) Consumption on Serum Interleukin-6 Levels and Health Status in Populations Living in the Peruvian Central Andes over 4000 m of Altitude. Plant Foods Hum Nutr. 2013 Aug 11 [Epub ahead of print]. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/23934543 (accessed 9/11/2013).

Gonzales, G.F., et al. 2002. Effect of Lepidium meyenii (MACA) on sexual desire and its absent relationship with serum testosterone levels in adult healthy men. Andrologia. 34(6): 367-72. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/12472620/ (accessed 9/11/2013).

Gonzales, G.F., et al. 2001. Lepidium meyenii (Maca) improved semen parameters in adult men. Asian J Androl. 3(4): 301-3. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/11753476 (acecssed 9/11/2013).

Mazaro-Costa, R., et al. 2010. Medicinal plants as alternative treatments for female sexual dysfunction: utopian vision or possible treatment in climacteric women? J Sex Med. 7(11): 3695-714. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/20722793 (accessed 9/11/2013).

Mehta, K., et al. 2007. Comparison of glucosamine sulfate and a polyherbal supplement for the relief of osteoarthritis of the knee: a randomized controlled trial [ISRCTN235438351]. BMC Complement Altnern Med. 7:34. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/17974032 (accessed 9/11/2013).

Meissner, H.O., et al. 2006. Hormone-Balance Effect of Pre-Gelatinized Organic Maca (Lepidium peruvianum Chacon): (I) Biochemical and Pharmocodynamic Study on Maca using Clinical Laboratory Model on Overiectomized Rats. Int J Biomed Sci. 2(3): 260-272. URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614604/ (accessed 9/11/2013).

Rowland, D.L. & Tai, W. 2003. A Review of Plant-Derived and Herbal Approaches to the Treatment of Sexual Dysfunctions. J Sex & Mar Ther. 29(3): 185-205. URL: http://redsaf.org/pipermail/red_redsaf.org/attachments/20071224/55893126/attachment-0018.pdf (accessed 9/11/2013).

Shin, B.C., et al. 2010. Maca (L. meyenii) for improving sexual function: a systematic review. BMC Comp & Alt Med. 10:44. URL: http://www.biomedcentral.com/1472-6882/10/44 (accessed 9/11/2013).

Stone, M., et al. 2009. A pilot investigation into the effect of maca supplementation on physical activity and sexual desire in sportsmen. J Ethonopharmacol. 126(3): 574-6. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/19781622/ (accessed 9/11/2013).

Valentova, K. & Ulrichova, J. 2003. Smallanthus sonchifolius and Lepidium meyenii – Prospective Andean Crops for the Prevention of Chronic Diseases. Biomed. Papers. 147(2): 119-130. URL: http://mefanet.upol.cz/BP/2003/2/119.pdf (accessed 9/11/2013).

Zenico, T., et al. 2009. Subjective effects of Lepidium meyenii (Maca) extract on well-being and sexual performances in patients with mild erectile dysfunction: a randomised, double-blind clinical trial. Andrologia. 41(2): 95-9. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/19260845 (accessed 9/11/2013).

Zhang, Y., et al. 2006. Effect of ethanol extract of Lepidium meyenii Walp. on osteoporosis in ovariectomized rats. J Ethnopharmacol. 105(1-2): 274-9. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/16466876 (accessed 9/11/2013).

Zheng, B.L., et al. 2000. Effect of a lipidic extract from lepidium meyenii on sexual behavior in mice and rats. Urology. 55(4): 598-602. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/10736519 (accessed 9/11/2013). Zhao, J., et al. 2005. New alkamides from maca (Lepidium meyenii). J Agric Food Chem. 53(3): 690-3. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/15686421 (accessed 9/11/2013).

Meston: http://homepage.psy.utexas.edu/homepage/group/mestonlab/publications/updatefsf.pdf Ginkgo: http://www.ncbi.nlm.nih.gov/pubmed/15378664 Genital responsiveness to testosterone: http://www.ncbi.nlm.nih.gov/pubmed/10665617

Muira Puama

Antunes, E., et al. 2001. The relaxation of isolated rabbit corpus cavernosum by the herbal medicine Catuama and its constituents. Phytother Res. 15(5): 416-21. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/11507734 (accessed 11.21.2013).

Correia, A.F., et al. 2008. Amazonian plant crude extract screening for activity against multidrug-resistant bacteria. European Review for Medical and Pharmacological Sciences. 12: 369-80. URL: http://www.researchgate.net/publication/23790255_Amazonian_plant_crude_extract_screening_for_activity_against_multidrug-resistant_bacteria/file/d912f50575859bd17f.pdf (accessed 11.21.2013).

da Silva, A.L., et al. 2002. Anxiogenic properties of Ptychopetalum olacoides Benth. (Marapuama). Phytotherapy Research. 16 (3): 223-226. URL (abstract): http://onlinelibrary.wiley.com/doi/10.1002/ptr.825/abstract (accessed 11.21.2013).

Figueiro, M., et al. 2011. The Amazonian herbal Marapuama attenuates cognitive impairment and neuroglial degeneration in a mouse Alzheimer model. Phytomedicine. 18(4): 327-33. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/20739160 (accessed 11.21.2013).

Firgueiro, M., et al. 2010. Acetylcholinesterase inhibition in cognition-relevant brain areas of mice treated with nootropic Amazonian herbal (Marapuama). Phytomedicine. 17(12): 956-62. URL (abstract): http://www.sciencedirect.com/science/article/pii/S0944711310000681 (accessed 11.21.2013).

Oliveira C.H., et al. 2005. Clinical toxicology study of an herbal medicinal extract of Paullinia cupana, Trichilia catigua, Ptychopetalum olacoides and Zingiber officinale (Catuama) in healthy volunteers. Phytother Res. 19(1):54-7. URL (abstract): http://www.ncbi.nlm.nih.gov/m/pubmed/15798997/ (accessed 11.21.2013).

Piato AL, et al. 2010. Anti-stress effects of the "tonic"Ptychopetalum olacoides (Marapuama) in mice. Phytomedicine. 2010. 17(3-4):248-53. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/19682881 (accessed 11/14/2013).

Piato AL, et al. 2009. Antidepressant profile of Ptychopetalum olacoides Bentham (Marapuama) in mice. Phytother Res. 23(4):519-24. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/19067380 (accessed 11/15/2013).

Piato AL, et al. 2008. Effects of Marapuama in the chronic mild stress model: further indication of antidepressant properties. J Ethnopharmacol.118(2):300-4. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/18513902 (accessed 11/15/2013).

Quintao, N.L.M., et al. 2008. Evaluation of the effects of the herbal product Catuama® in inflammatory and neuropathic models of nociception in rats. Phytomedicine. 15(4): 245-52. URL (abstract): http://www.sciencedirect.com/science/article/pii/S0944711307000554 (accessed 11/21/2013).

Shah, G. R., et al. 2012. Evaluation of a multi-herb supplement for erectile dysfunction: a randomized double-blind, placebo-controlled study. BMC Complement Altern Med. 12: 155. URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478157/ (accessed 11.21.2013).

Siqueira IR, et al. 2007. Antioxidant activities of Ptychopetalum olacoides ("muirapuama") in mice brain. Phytomedicine. 14(11):763-9. URL (abstract): http://www.ncbi.nlm.nih.gov/m/pubmed/17433649/ (accessed 11.21.2013)

Siqueira IR, et al. 2003. Ptychopetalum olacoides, a traditional Amazonian "nerve tonic", possesses anticholinesterase activity. Pharmacol Biochem Behav. 75(3):645-50. URL (abstract): http://www.ncbi.nlm.nih.gov/m/pubmed/12895682/ (accessed 11.21.2013)

Waynburg, J. & Brewer, S. 2000. Effects of Herbal vX on libido and sexual activity in premenopausal and postmenopausal women. Advances in Therapy. 17 (5): 255-262. URL (abstract): http://link.springer.com/article/10.1007/BF02853164 (accessed 11.21.2013).


Adaikan PG, et al. 2000 Proerectile pharmacological effects of Tribulus terrestris extract on the rabbit corpus cavernosum. Ann Acad Med Singapore.29(1):22-6. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/10748960 (accessed 11/15/2013).

Brown, G.A., et al. 2001. Endocrine and lipid responses to chronic androstenediol-herbal supplementation in 30 to 58 year old men. J Am Coll Nutr. 20(5): 520-8. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/11601567 (accessed 11.21.2013).

Brown, G.A., et al. 2000. Effects of anabolic precursors on serum testosterone concentrations and adaptations to resistance training in young men. Int J Sport Nutr Exerc Metab. 10(3): 340-59. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/10997957 (accessed 11.21.2013).

Gauthaman, K. & Ganesan, A.P. 2008. The hormonal effects of Tribulus terrestris and its role in the management of male erectile dysfunction--an evaluation using primates, rabbit and rat. Phytomedicine. 15(1-2):44-54. URL: http://www.ncbi.nlm.nih.gov/m/pubmed/18068966/ (accessed 11.21.2013).

Gauthaman, K. & Adaikan, P.G. 2005. Effect of Tribulus terrestris on nicotinamide adenine dinucleotide phosphate-diaphorase activity and androgen receptors in rat brain. J Ethnopharmacol. 96(1-2):127-32. URL (abstract): http://www.ncbi.nlm.nih.gov/m/pubmed/15588660/ (accessed 11.21.2013).

Gauthaman K, et al. 2003. Sexual effects of puncturevine (Tribulus terrestris) extract (protodioscin): an evaluation using a rat model. J Altern Complement Med.9(2):257-65. URL (abstract): http://www.ncbi.nlm.nih.gov/m/pubmed/12804079/ (accessed 11.21.2013).

Iacono, F., et al. 2012. Sexual asthenia: Tradamixina versus Tadalafil 5 mg daily. BMC Surg. 12 Suppl 1:S23. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/23173697 (accessed 11.21.2013).

Iocono, F., et al. 2012. Observational study: daily treatment with a new compound “Tradamixina” plus serenoa repens for two months improved lower urinary tract symptoms. BMC Surg. 12 Suppl 1:S22. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/23173650 (accessed 11.21.2013).

Kam SC, et al. 2012. In vivo and in vitro animal investigation of the effect of a mixture of herbal extracts from Tribulus terrestris and Cornus officinalis on penile erection. J Sex Med. 9(10):2544-51. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/22906304 (accessed 11/15/2013).

Milasius K, et al. 2009. The influence of the Tribulus terrestris extract on the parameters of the functional preparedness and athletes' organism homeostasis. Fiziol Zh. 55(5):89-96URL (abstract): http://www.ncbi.nlm.nih.gov/m/pubmed/20095389/ (accessed 11.21.2013)

Neychev, V.K. & Mitev, V.I. 2005. The aphrodisiac herb Tribulus terrestris does not influence the androgen production in young men. J Ethnopharmacol. 101(1-3): 319-23. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/15994038 (accessed 11.21.2013).

Riaz, A., et al. 2010. Assessment of acute toxicity and reproductive capability of a herbal combination. Pak J Pharm Sci. 23(3): 291-4. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/20566442 (accessed 11.21.2013).

Rogerson, S., et al. The effect of five weeks of Tribulus terrestris supplementation on muscle strength and body composition during preseason training of elite rugby league players. J Strength Cond Res. 21(2): 348-53. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/17530942 (accessed 11.21.2013).

Saudan, C., et al. 2008. Short term impact of Tribulus terrestris intake on doping control analysis of endogenous steroids. Forensic Sci Int. 178(1): e7-10. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/18282674 (accessed 11.21.2013).


Amieva, H., et al. 2013. Ginkgo Biloba Extract and Long-Term Cognitive Decline: A 20-Year Follow-Up Population-Based Study. PLoS One. 8(1): e52755. URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543404/ (accessed 11.21.2013).

Barton, D.L., et al. 2013. The use of Ginkgo biloba for the prevention of chemotherapy-related cognitive dysfunction in women receiving adjuvant treatment for breast cancer, N00C9. Support Care Cancer. 21(4): 1185-92. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/23150188 (accessed 11.21.2013).

Bhidayasiri, R., et al. 2013. Evidence-based guideline: treatment of tardive syndromes: report of the Guidelines Development Subcommittee of the American Academe of Neurology. Neurology. 81(5): 463-9. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/23897874 (accessed 11.21.2013).

Evans, J.R. 2013. Ginkgo biloba extract for age-related macular degeneration. Cochrane Database Syst Rev. 1: CD001775. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/23440785 (accessed 11.21.2013).

Paick JS & Lee JH. 1996. An experimental study of the effect of ginkgo biloba extract on the human and rabbit corpus cavernosum tissue. J Urol.156(5):1876-80. URL (abstract): http://www.ncbi.nlm.nih.gov/m/pubmed/8863636/ (accessed 11.21.2013)

Mathis, C.A., et al. 2013. In vivo assessment of amyloid-B deposition in nondemented very elderly subjects. Ann Neurol. 73(6): 851-61. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/23596051 (accessed 11.21.2013).

Nasab, N.M., et al. 2012. Efficacy of rivastigmine in comparison to ginkgo for treating Alzheimer’s dementia. J Pak Med Assoc. 62(7): 677-80. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/23866514 (accessed 11.21.2013).

Nicolai, S.P., et al. 2013. Ginkgo biloba for intermittent claudication. Cochrane Database Syst Rev. 6 CD006888. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/23744597 (accessed 11.21.2013).

Rainer, M., et al. 2013. Ginkgo biloba extract Egb 761 in the treatment of dementia: a pharmacoeconomic analysis of the Austrian setting. Wien Klin Wochenschr. 125(1-2): 8-15. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/23292640 (accessed 11.21.2013).

Vellas, B., et al. 2012. Long-term use of standardised Ginkgo biloba extract for the prevention of Alzheimer’s disease (GuideAge): a randomized placebo-controlled trial. Lancet Neurol. 11(10): 851-9. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/22959217 (accessed 11.21.2013).

Zhang, W.F., et al. 2011. Extract of Ginkgo biloba treatment for tardive dyskinesia in shcizophrenia: a randomized, double-blind, placebo-controlled trail. J Clin Psychiatry. 72(5): 615-21. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/20868638 (accessed 11.21.2013).


Agarwal, S. P., et al. 2007. Shilajit: a review. Phytother Res., 21: 401–405. URL (abstract): http://onlinelibrary.wiley.com/doi/10.1002/ptr.2100/abstract (accessed 11.24.2013.)

Biswas, T.K., et al. 2010. Clinical evaluation of spermatogenic activity of processed Shilajit in oligospermia. Adrologia. 42(1): 48-56. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/20078516 (accessed 11.22.2013).

Carrasco-Gallardo, C., et al. 2012. Shilajit: A Natural Phytocomplex with Potential Procognitive Activity. Int J Alzheimers Dis. 2012: 674142. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296184/ (accessed 11.22.2013).

Carrasco-Gallardo, C., et al. 2012. Can nutraceuticals prevent Alzheimer’s disease? Potential therapeutic role of a formulation containing shilajit and complex B vitamins. Arch Med Res. 43 (8): 699-704. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/23131823 (accessed 11.22.2013).

Ghosal, S., et al. 1989. Mast cell protecting effects of shilajit and its constituents. Phytother Res. 3: 249–252. URL (abstract): http://onlinelibrary.wiley.com/doi/10.1002/ptr.2650030606/abstract (accessed 11.24.2013).

Goel, R.K., et al. 1990. Antiulcerogenic and anti-inflammatory studies with shilajit. J Ehtnopharmacol. 29 (1): 95-103. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/2345464 (accessed 11.22.2013).

Mohamed-I, K., et al. 2012. Anti-Microbial, Anti-Oxidant and Anti-Ulcerogenic Effects of Shilajit on Gastric Ulcer in Rats. American Journal of Biochemistry and Biotechnology. 8 (1): 26-39, 2012. URL (abstract) http://www.thescipub.com/abstract/10.3844/ajbbsp.2012.26.39 (accessed 11.24.2013)

Park, J.S., et al. 2006. The spermatogenic and ovogenic effects of chronically administered Shilajit to rats J Ethnopharmacol. 107(3): 349-53. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/16698205 (accessed 11.22.2013).

Sharma, P., et al. 2003. Shilajit: evalution of its effects on blood chemistry of normal human subjects. Anc Sci Life. 23(2):114-9. URL (abstract) http://www.ncbi.nlm.nih.gov/pubmed/22557121 (accessed 11.24.2013)

Stohs, S.J. 2013. Safety and Efficacy of Shilajit (Mumie, Moomiyo). Phytother Res. doi: 10.1002/ptr.5018. [Epub ahead of print]. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/23733436 (accessed 11.22.2013).

Velmurugan, C., et al. 2012. Evaluation of safety profile of black shilajit after 91 days of repeated administration in rats. Asian Pac J Trop Biomed. 2(3): 201-4. doi: 10.1016/S221-1691(12)60043-4 URL (abstract) http://www.ncbi.nlm.nih.gov/pubmed/?term=evaluation+and+safety+profile+of+black+shilajit (accessed 11.22.2013).

Wilson, E., et al. 2011. Review on shilajit used in traditional Indian medicine. J Ethnopharmacol. 136(1): 1-9. URL (abstract): http://www.ncbi.nlm.nih.gov/pubmed/21530631 (accessed 11.22.2013).

Average Ratings

88% recommend Arginelle

Overall Rating:
Customer Service:

Showing 1-10 of 26 reviews

Review by Sightseer on 10/31/2016

Would Recommend: Yes
Overall Rating:
Customer Service:

Review by Marianne on 09/09/2016

Would Recommend: Yes
Overall Rating:
Customer Service:
It really works to improve your libido. I noticed the very first day after taking two1

Review by MaggieO on 07/13/2016

Would Recommend: Yes
Overall Rating:
Customer Service:
OMG this is the female Cialis. I had a hysto over 10yrs ago and have been dry ever since. This actually solves that problem - totally. I love that you can take a few more to help in a jiffy or you can stay constant with your daily dose. My husband has commented on how much better I feel and seem to enjoy our time again. No irritation or messy creams

Review by SHAMM on 06/20/2016

Would Recommend: Yes
Overall Rating:
Customer Service:

Review by Maureen on 05/09/2016

Would Recommend: Yes
Overall Rating:
Customer Service:

Review by Kim on 04/05/2016

Would Recommend: Yes
Overall Rating:
Customer Service:

Review by Jennifer on 04/04/2016

Would Recommend: Yes
Overall Rating:
Customer Service:
As a post menopausal woman, it helps with dryness.

Review by Melissa on 03/21/2016

Would Recommend: Yes
Overall Rating:
Customer Service:

Review by Martha on 03/17/2016

Would Recommend: Yes
Overall Rating:
Customer Service:
This works! This made a huge difference in my libido and sex drive, however I had to stop taking it because the Maca Root that is in it interferes with my bi-polar. It gives me the jitters and makes me anxious. I am crushed that I cannot take this anymore because it really ramped up my sex drive. I would highly recommend giving this supplement a spin, it made a difference for me. It only took a week and I could tell a difference, it also helps with orgasms, at least it did with me.

Review by okiedokie on 08/27/2015

Would Recommend: No
Overall Rating:
Customer Service:
This product has lots of good stuff in it and gave me more general energy but did not have the affect on my libido I was hoping for.